Detalles de la búsqueda
1.
Combinatorial targeting of G-protein-coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug-induced liver injury.
Hepatology;
78(1): 26-44, 2023 07 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36107019
2.
Atorvastatin protects against liver and vascular damage in a model of diet induced steatohepatitis by resetting FXR and GPBAR1 signaling.
FASEB J;
36(1): e22060, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34862975
3.
The bile acid activated receptors GPBAR1 and FXR exert antagonistic effects on autophagy.
FASEB J;
35(1): e21271, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33368684
4.
The Bile Acid Receptor GPBAR1 Modulates CCL2/CCR2 Signaling at the Liver Sinusoidal/Macrophage Interface and Reverses Acetaminophen-Induced Liver Toxicity.
J Immunol;
204(9): 2535-2551, 2020 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32213564
5.
Bile acids serve as endogenous antagonists of the Leukemia inhibitory factor (LIF) receptor in oncogenesis.
Biochem Pharmacol;
223: 116134, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38494064
6.
Modeling Inflammatory Bowel Disease by Intestinal Organoids.
Recent Adv Inflamm Allergy Drug Discov;
17(1): 39-53, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-36411558
7.
Discovery of a Novel Class of Dual GPBAR1 Agonists-RORγt Inverse Agonists for the Treatment of IL-17-Mediated Disorders.
ACS Omega;
8(6): 5983-5994, 2023 Feb 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-36816679
8.
Combinatorial therapy with BAR502 and UDCA resets FXR and GPBAR1 signaling and reverses liver histopathology in a model of NASH.
Sci Rep;
13(1): 1602, 2023 01 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-36709356
9.
Correction to "Discovery of a Novel Class of Dual GPBAR1 Agonists-RORγt Inverse Agonists for the Treatment of IL-17-Mediated Disorders".
ACS Omega;
8(47): 45163, 2023 Nov 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-38046314
10.
Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinoma.
Front Oncol;
13: 1140730, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-36998446
11.
Defective Bile Acid Signaling Promotes Vascular Dysfunction, Supporting a Role for G-Protein Bile Acid Receptor 1/Farnesoid X Receptor Agonism and Statins in the Treatment of Nonalcoholic Fatty Liver Disease.
J Am Heart Assoc;
12(23): e031241, 2023 Dec 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37996988
12.
The leukemia inhibitory factor regulates fibroblast growth factor receptor 4 transcription in gastric cancer.
Cell Oncol (Dordr);
2023 Nov 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37945798
13.
Activation of GPBAR1 attenuates vascular inflammation and atherosclerosis in a mouse model of NAFLD-related cardiovascular disease.
Biochem Pharmacol;
218: 115900, 2023 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37926268
14.
Organoids as ex vivo culture system to investigate infection-host interaction in gastric pre-carcinogenesis.
Recent Adv Inflamm Allergy Drug Discov;
2022 Jan 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34986780
15.
Next-Generation Sequencing Analysis of Gastric Cancer Identifies the Leukemia Inhibitory Factor Receptor as a Driving Factor in Gastric Cancer Progression and as a Predictor of Poor Prognosis.
Front Oncol;
12: 939969, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35847866
16.
Discovery of a Potent and Orally Active Dual GPBAR1/CysLT1R Modulator for the Treatment of Metabolic Fatty Liver Disease.
Front Pharmacol;
13: 858137, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35559268
17.
GLP-1 Mediates Regulation of Colonic ACE2 Expression by the Bile Acid Receptor GPBAR1 in Inflammation.
Cells;
11(7)2022 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35406751
18.
Beneficial effects of UDCA and norUDCA in a rodent model of steatosis are linked to modulation of GPBAR1/FXR signaling.
Biochim Biophys Acta Mol Cell Biol Lipids;
1867(11): 159218, 2022 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-35985473
19.
Repositioning Mifepristone as a Leukaemia Inhibitory Factor Receptor Antagonist for the Treatment of Pancreatic Adenocarcinoma.
Cells;
11(21)2022 11 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36359879
20.
Discovery of a AHR pelargonidin agonist that counter-regulates Ace2 expression and attenuates ACE2-SARS-CoV-2 interaction.
Biochem Pharmacol;
188: 114564, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33872570